40 Hz light for stimulation of gamma brainwaves
40 Hz light for gamma stimulation has been shown to improve memory and cognitive performance in a mouse model of Alzheimer's disease. 40 Hz light stimulation reduced amyloid plaque associated with Alzheimer's disease in the brain of mice by about 50%.
Optoceutics develops a masked 40 Hz light that removes the stroboscopic effect from normal stroboscopic 40 Hz light while retaining the stimulation effect on the brain. However the potential for treatment and prevention of human diseases has not yet been investigated.
Clinical trials are ready to start in 2020 to validate the impact on Alzheimer's disease.
Frequently asked questions
What is the science behind?
The latest study of light therapy and Alzheimer's disease appeared in the journal Nature in 2016 entitled Gamma frequency entrainment attenuates amyloid loading and alters microglia . Be aware that although the experiments showed positive results on amyloid beta and cognitive ability, it is still only detected in mice. Whether the beneficial effects of gamma-light therapy can have far-reaching effects on other brain regions involved in Alzheimer's disease remains an open possibility for investigation.
What is Amyloid Beta?
Amyloid beta (sometimes called beta-amyloid or β-amyloid or Aβ) is a neural peptide or strict amino acid that has been shown to aggregate or "clump" in Alzheimer's disease. While it is not clear whether amyloid beta is the cause of the disease, or perhaps a mechanism to combat it, there is a strong correlation between the severity of the disease and the amount of amyloid beta in the brain. For this reason, a huge amount of resources have been spent on developing therapies designed to reduce the accumulation of amyloid beta in the brain. Some of these treatments are currently undergoing clinical trials, including gamma therapy.
What is gamma stimulation?
The gamma brain frequency is often used in neuroscience and physiology to represent phenomena that occur approximately 40 times per second, or 40 Hertz (Hz). It is not known why the gamma frequency activates these cellular processes, but probably represents a complex phenomenon with both large-scale neuronal networks and subcellular interactions. This scale problem represents one of the most intriguing junctions in the field of neuroscience, but unfortunately leaves many questions open about the significance of gamma frequency. Importantly, frequencies outside the gamma range of 40 Hz have been shown not to have the same effect with regard to clearance of amyloid beta.
January 28, 2020
TV2 Lorry has followed us for a long time in connection with our participation in the Danish Tech Challenge.
We are very pleased with the great media coverage we have been given, so that we can get more focus on this still unresolved big challenge.
Danish Tech Challenge Awardshow
January 23, 2020
As finalists in the Danish Tech Challenge, we participated in a blast of an award show, which was hosted by, among others, HKH Crown Prince Frederik.
* TV2 Lorry Spoilers in advance *
Unfortunately it did not turn into a 1st place for us, but the competition was fierce among some other fantastic companies.
Congratulations to Pentalock on their well-deserved victory!
Thank you to the team behind the Danish Tech Challenge and all our other startup colleagues
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